Composition: Each 5 gm contains: Piperazine citrate 0.165 gm. Colchicine 0.3 mg. Khellin 1.75 mg. Atropine sulphate 0.128 mg. Citric acid anhydrous Q.S. Sodium bicarbonate Q.S. Properties: Colchicine is used for the relief of acute gout and prophylaxis of acute attacks Colchicine produces a dramatic response in acute gout by giving rapid relief from pain and reducing the inflammatory reaction to urate crystals. The effect might be due to several actions including decreased mobility of leucocytes. Piperazine citrate has been reported to produce an apparent decrease in measurements of serum uric acid. • Khellin and Atropine sulphate, by their relaxant action, relieve urinary tract spasm during excretion of urates. • Sodium bicarbonate is an alkalinising agent since alkaline urine is essential to prevent development of uric acid renal calculi. Indications And Usage: Acute and chronic gout Gouty arthritis Prophylaxis against urate stones Contraindications Known hypersensitivity to any of the components Blood dyscrasias Pregnancy Acute dehydration, anuria or hyperkalemia Adverse Reactions: Occasionally nausea, vomiting, abdominal pain and diarrhea may occur. Dosage & Administration: One sachet (5 gm) in a half glass of water before meals T.D.S. or as prescribed by the physician. Precautions: Used with caution: In patient with serious GI., renal, hepatic, and cardiovascular disorders. In children, geriatrics, debilitated patients and nursing women. Package: Box of 10 sachets x 5 gm.